… complex to a cognate T cell receptor (TCR) (Figure 3, box 4). … compensatory mutations that
are associated with CD8+ T cell-… immunodeficiency virus-specific CD8 + T-cell responses …

… response-associated mutations of the viruses from the single-… T-cell recognition by T-cell
receptors (9, 14, 15). However, several virus-specific CTL epitopes can be recognized by T cells …

… Virus-specific CD8+ T-cells play a major role in viral clearance … viral mutations leading to
escape from the CD8+ T-cell … tases with autologous T cell receptor redirected T cells, targeting …

… Superinfection of chronic hepatitis B with the hepatitis D virus … /epitope multimers to the
T-cell receptor allows the ex vivo … Here, we propose that viral escape mutations with reduced or …

… studies demonstrated that in acute self-limited HBV infection, both CD8 + T cell and CD4 +
… Such chronic presentation of viral antigens progressively suppresses virus-specific T cell …

… phenotypic profiles and T cell receptor (TCR) … viral mutation and tetramer response on
this given epitope (fig. S14B), showing that these HBV-specific CD8 + T cells can recognize …

… , patients with chronic HBV infection have severe quantitative … –electroporated T cells to
recognize different viral mutants was … T cells (6) and the ability of HBV c18 CD8 + T cell lines to …

… on an effective virus-specific CD8+ T-cell response; however… downregulation and
internalization of the T-cell receptor (TCR) as … did not display mutations in the epitopes targeted in …

… CD4 and CD8 T cell responses in acute resolving infection compared with … , we observed a
broad pattern of recognition covering all HBV proteins, with single … Hepatitis B virus infection …

… after the introduction of virus-specific CD8 cells supports this … to revive virus-specific T cell
responses. These policies treat … impact on viral persistence by modifying virus-specific immune …